Which drugs to fight androgenetic alopecia (AAG)?
Androgenetic alopecia is the leading cause of gradual hair loss in men, less common in women.
It is due to the influence of male hormones (androgens, DHT).
The androgen inhibitor medicine can correct the cause, and stop hair loss, but if it must be taken continuously (Stopping treatment will stop the effects).
In all cases, it is recommended to consult a doctor before opting for drug treatment.
For other types of alopecia, read here.
Minoxidil, Finasteride and other drugs: how effective?
The drugs can stop the process of hair loss, and in some cases achieve regrowth of follicular units affected by alopecia.
This is particularly the case for thinning hair, which can perfectly regain good density.
The drugs are most effective in young patients (20 to 30 years old) and for relatively moderate hair loss, and are of no benefit in patients with very advanced stable baldness.
The other advantage is that they make it possible to prepare for the success of a subsequent transplant, because the implanted grafts will grow back much more surely.
The most famous surgeons generally only accept patients who are undergoing medical treatment for a year or 6 months before the transplant.
What is the best cocktail of treatments for hair loss in men?
- Minoxidil in lotion (at a concentration of 2 or 5% for men) is is a vasodilator that promotes micro circulation in the scalp; generally combined with Finasteride, Latanaprost, Prostaquinone, and sessions of mesotherapy and light therapy.
- Finasteride tablets are considered to be the most effective, but the risk of loss of libido, decrease in sexual function in men, in 1 to 10% of cases, is enough to discourage a good number of patients from taking this treatment.
- Finasteride lotion (Topical Finasteride, 0.25%), applied to the hair like Minoxidil, does not have the feared side effects, however its results have not yet been scientifically proven and therefore its marketing is still limited.
- Dutasteride is sometimes used as an alternative to Finasteride.
- or dietary supplements, such as Saw Palmetto, or AlphaRegul from ARLOR laboratories (available in tablets, lotions, shampoos)
- or Spironolactone: in applications, also produces anti-androgenic effects
Treatment for andro-genetic alopecia in women
- Minoxidil: in topical form, concentration 2%, diluted in a fatty substance (propylene glycol), therefore women are often reluctant to use it.
- Finasteride: contraindicated, because risk of malformation of the fetus in the event of pregnancy
- Other anti-androgens: Cyproterone acetate, Spironolactone, Cimetidine, Ketoconazole (shampoo)
- Low dosage oral contraceptives (Ethinyloestradiol): they can block the action of male hormones, especially in combination with cyproterone acetate.
- Estrogen progestins: in women with menopause, estrogen and progesterone (pills, creams) are commonly prescribed as a treatment for androgenetic alopecia.
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